Scientists typically optimize assay parameters first, then select an automated liquid handler using default parameters during transition to an automated platform. This study illustrates the importance of optimizing both the assay and any associated liquid handling steps with the goal of minimizing variability.
This tutorial demonstrates the importance of understanding the assay technicalities that should be taken into consideration before automated scripts are created to prepare for potential challenges encountered during method transfer.
As more and more researchers move to sub-10 μL reaction volumes in their genomics workflows, it will become more critical than ever before to ensure highly precise liquid handling within these volume ranges. The MANTIS can be easily added to any traditional liquid handling workstation in order to obtain CV’s under 2% across the entire pipetting range.
This application note provides performance testing results obtained at the low volume range capability of Beckman Coulter’s Biomek i-Series Automated Workstation. The Artel MVS was used to measure the delivered volumes and to facilitate the optimization of pipetting techniques through Biomek Software.
This poster presents two major findings. First, how to study liquid handlers as part of a system within the context of the assay being optimized. Second, it was possible to further optimize the overall performance of the assay by not only optimizing the liquid handlers, but by choosing the correct liquid handler-reagent pairing.
This presentation covers how volumetric performance and regulatory standards overlap, focusing on the biggest takeaways from the new ISO/IWA 15 agreement. This agreement was developed by expert participants from 18 different leading liquid handling organizations including equipment manufacturers, user laboratories, and third party testing services.
This study uses a two factor design (temperature and humidity) to investigate volumetric performance (precision and trueness) at environmental conditions from 15 °C to 30 °C and 30% to 80% relative humidity. Nine environmental conditions were tested, the mid point, four corner cases and four edge cases. Replicate testing was performed at the mid point and corner cases.