Overview

Artel Accredited Calibration Service Overview

Your results can change lives. You need the utmost confidence in your data, and a critical part of that confidence comes from instrument calibrations that meet regulatory requirements. Artel is now ready to help you meet your automated liquid handler calibration needs with the first and only ISO 17025 accredited service.

Save money on expensive service contracts

Save money on expensive service contracts


— knowing that your liquid handler is performing well can give you the confidence to minimize your purchase of expensive service contracts.

Easily meet regulatory requirements<br />

Easily meet regulatory requirements


— leave your liquid handler calibration to the only service provider that is accredited to ISO 17025:2005.

Bring your liquid handlers back online faster

Bring your liquid handlers back online faster


— have an Artel specialist perform volume verifications for new and newly-serviced instruments and minimize instrument downtime.

Get more use out of your current liquid handlers

Get more use out of your current liquid handlers


— knowing how your instrument is truly performing can give you the confidence you need in your low-liquid volume assays.

Leverage Artel experience

Leverage Artel experience


— the Artel Accredited Calibration Service team has years of combined experience performing regulatory-compliant calibrations on all makes and models of liquid handlers.

Stay productive and focused on your work

Stay productive and focused on your work


— remove the distractions of maintaining liquid handling quality and keep your team focused WORK on the work that matters most.

How it works

How the Service Works

Getting a calibration certificate for your automated liquid handler has never been so easy.

With the Artel Accredited Calibration Service, an Artel specialist comes to your lab with all the necessary NIST-traceable calibration equipment and performs an as-found calibration of your automated liquid handlers.

Step 1: Call to schedule a service

When you reach out to the Artel Accredited Calibration Service team, an Artel specialist will discuss and assess your needs and develop a plan for the service visit. The Accredited Calibration Service team has extensive experience verifying the performance of automated liquid handlers, such as these commonly used models, and many more.

  • Tecan (Freedom Evo, HP D300)
  • Labcyte (Echo)
  • Hamilton (Star)
  • Eppendorf (epMotion)
  • Agilent (Bravo)
  • Beckman (NX, FX, 3000/4000)

Step 2: An Artel specialist visits your lab

During the on-site service, your Artel specialist will come fully equipped to calibrate your automated liquid handlers.

Step 3: You get a calibration certificate

Upon successful calibration, you will receive a calibration certificate from our ISO 17025:2005-accredited team.

Meet the team

Meet the Artel Accredited Calibration Service Team

Staying regulatory-compliant doesn’t have to mean sacrificing speed

Artel understands that every minute your automated liquid handler (ALH) spends being calibrated means a delay of often critical test results, which is why Artel’s Accredited Calibration Service team delivers fast and efficient ALH calibration services. Built on a strong foundation of calibration experience and professionalism, our team’s focus on calibration directly translates into minimal interruptions of your testing timelines.

Kristi Allen

Kristi Allen

Kristi is an expert in laboratory quality control with determination in streamlining and implementing new processes. As the Laboratory Chemist Supervisor, Kristi is trained and qualified to comply with the requirements of ISO/IEC 17025. Her responsibilities include ensuring the quality of manufacturing reagents, final inspection of the PCS and MVS systems and reagents, as well as calibration, maintenance, troubleshooting and repair of laboratory equipment. Kristi is also part of a technical team delivering Artel Liquid Handling Services and ISO/IEC 17025 Accredited Liquid Handling System Calibrations in the real conditions of customers’ labs.

Mike Grimaldi

Mike Grimaldi

As a member of the Artel Quality Control department, Michael works as a Laboratory Chemist. His primary responsibilities include manufacturing and testing MVS/PCS solutions, calibrating MVS/PCS systems and calibration of laboratory equipment. Michael is trained and qualified to comply with the requirements of ISO/IEC 17025 and is also a member of the Artel Liquid Handling Service team. In addition, Michael has several years of experience in research labs including 5 plus years managing an academic research lab at Massachusetts General Hospital.

Rachel Parshley

Rachel Parshley

As a Product Development Scientist on the R&D team at Artel, Rachel Parshley has managed important product enhancement projects, including the development of 100% DMSO solutions for use with the MVS. Rachel is also part of a technical team delivering Artel Liquid Handling Service in the real conditions of customers’ labs.

Kim-Baisley

Kimberly Baisley

Kimberly works as a Laboratory Chemist for Artel in the Quality Control Department. Her responsibilities are to ensure product quality by performing calibrations and inspections of PCS and MVS systems, as well as manufacturing and testing PCS and MVS reagents. Kimberly is trained and qualified to comply with the requirements of ISO/IEC 17025. She applies her skills and knowledge from her several years of experience with working in the quality control industry. Kimberly is also part of the technical team delivering the Artel Liquid Handling Service.

FAQs

Artel Accredited Calibration Service Frequently Asked Questions


What is the Artel Accredited Calibration Service?

The Artel Accredited Calibration Service is an on-site ISO 17025 accredited calibration service for liquid handlers. Work with an ISO 17025 qualified scientist who will collect as-found, in-process, and as-left calibration data while your scientists adjust the liquid handlers. The calibration service follows ISO/IWA 15, uses NIST traceable equipment, and provides calibration certificates for each test.

↑ Back to top


What is the Artel Liquid Handling Service?

The Artel Liquid Handling Service is an on-site verification service. An experienced scientist brings equipment and supplies to troubleshoot, test, and verify your liquid handlers. Test at any volume, method, and/or labware to optimize or troubleshoot any automated liquid handler capable of dispensing into a mircrotiter plate.

↑ Back to top


What are the advantages of Artel Liquid Handling Service?

Artel Liquid Handling Service is faster than other services, provides you with expert Artel scientists and employs Artel technology – the acknowledged global measurement standard. Artel technology provides NIST-traceable volume measurements, whereby the volume transfer tests can be directly compared regardless of liquid handler make, model, location, or operator. Test reports, which include well-by-well and tip-by-tip measured volumes, are supplied during or immediately following the service event. Where applicable or required, summary tables and trending plots can be created. The test reports are available in HTML format and can be opened in Explorer, Excel or other spreadsheet programs. Alternatively, XML-tagged test reports can be fed into your LIMS.

Our mission is to help you meet your quality, productivity and compliance requirements. As the volume measurement experts, our professional, efficient, organized service team will communicate directly with you before, during and after the service event.

↑ Back to top


What is included in an Artel Liquid Handling Service visit?

Your service plan will be customized to meet your laboratory’s needs, and can cover such areas as:

  • liquid handler tip configuration(s), target volumes of interest, plate type, number of replicates per tip, etc.;
  • evaluating pipetting techniques, methodologies or even different tip types (forward vs. reverse mode; air gap usage; wet vs. dry dispensing; sequential dispense vs. single dispense, etc.);
  • directly comparing multiple liquid handlers under the same test conditions;
  • liquid handler performance for low-volume DMSO transfers;
  • facilitating method transfer from one liquid handler to another;
  • determining the best liquid handler for a specific task;
  • and many others.

↑ Back to top


How is liquid handler performance verified/calibrated?

Artel Liquid Handling Service uses the Artel MVS to measure volumes of solution delivered by the instruments under test. The MVS employs a dual-dye, ratiometric absorbance-based measurement method for calculating the volume of sample dispensed into a well of a microplate. The results of the verification tests are traceable to national and international standards.

Specially formulated sample solutions containing dyes of known concentration are dispensed into Artel verification plates – specialized microplates with dimensionally-characterized wells. Plates are mixed on a plate shaker to ensure homogeneity of samples. Absorbance readings are taken in the plate reader at 520 nm and 730 nm and a summary report containing the calculated dispensed volume for each dispensing tip is created.

Accuracy and precision of the dispensed volumes are measured against user-defined tolerance limits and failing values are flagged in the report. Summary statistics by well, by row, and by column are also contained in the summary report. Results are saved in a secured database and are available for printout or export in HTML or XML format.

↑ Back to top


What are the advantages of Artel measurement technology over other volume verification methods?

Artel technology provides analysis of accuracy and precision for each independent dispensing channel simultaneously, which saves labor and liquid handler down-time. The technology is virtually immune to environmental conditions and provides traceable measurements. The sample solutions are manufactured by Artel to precise tolerances using ISO-acknowledged methods. There is no need to generate standard curves. The technology provides standardized results making it possible to compare instrument performance between makes and models of liquid handlers as well as between locations, i.e., 2 µL dispensed by liquid handler X on Tuesday in Boston can be directly compared to 2 µL dispensed by liquid handler Y on Friday in San Diego. Compared to other methods, more testing events can be conducted in a shorter period of time with standardized, accurate results.

↑ Back to top


Can Artel Liquid Handling Service be used to verify any liquid handler?

Yes, Artel can assess, calibrate, optimize and document the performance of virtually any liquid handler that is capable of dispensing into a standard 96- or 384-well microplate.

↑ Back to top


Will I need to allocate any of my own personnel or labware resources?

A person from your laboratory, who is proficient in the operation of each liquid handler being tested, will be required to work with the Artel applications specialist during the service visit. Disposable tips, system fluid, pumps, source reservoirs, and other labware required for the specific liquid handler, must be supplied by your laboratory. Artel provides all testing solutions and microplates required.

 

↑ Back to top


What will I need to purchase?

Artel Liquid Handling Service is available in 8-hour, daily increments. Costs to you include:

  • the per day charge, plus travel and living costs for the Artel applications specialist, and
  • the time required for your automation-proficient technician to work with the Artel applications specialist for the duration of the service visit.

At the conclusion of the service event, Artel will provide a complete summary of the testing which includes summary tables and data in electronic form. Additionally, at your request, we can review the overall testing results with your key stakeholders.

↑ Back to top


How many liquid handlers can be tested in one day?

This depends on your lab’s needs, and your specific goals. For instance, your prime concern may be well-characterized, scheduled performance verification for regulatory compliance. On the other hand, you may be engaged in a complex and critical method transfer that you would like to optimize. With your primary requirement as a framework, the number of liquid handlers that can be processed is then dependent on:

  • the length of time required to execute the liquid handler method for the test solution and diluent buffer additions;
  • the number of methods/robots to test;
  • the amount of replicate testing events required;
  • time required to fix/optimize a method/robot; and
  • any unexpected events that may affect the testing process.

↑ Back to top


Can I schedule Artel to come periodically to verify the performance of my liquid handler(s)?

Yes, Artel Liquid Handling Service can be purchased one day at a time or, alternatively, can be contracted for periodic frequencies (weekly, monthly, quarterly, etc.) to satisfy your liquid handling quality requirements.

↑ Back to top


What are the specifications for accuracy and precision of the measurements?

The Artel technology performance claims may be viewed here. For a detailed uncertainty budget, please contact Technical Support.

↑ Back to top


Can an Artel Liquid Handling Service calibrate multichannel pipettes?

Many quality-minded labs use the Artel MVS for calibration of their multichannel pipettes. However, Artel does not offer a service for calibration of these instruments at this time.

↑ Back to top


Is the measurement technology FDA approved?

The technology is not subject to FDA approval because it is not directly associated with human samples or specimens. However, all measurement results are traceable to national and international standards.

↑ Back to top


Why is liquid handling quality assurance important?

Superior liquid handling quality assurance leads to superior assay data. Read more about the  importance of liquid handling quality assurance.

↑ Back to top


Does Artel provide liquid handler methods?

No, Artel does not provide liquid handler methods.

↑ Back to top