Accuracy vs. Precision: Distinct Terms with Implications for Liquid Handling

A conversation with George Rodrigues, PhD, Senior Scientific Manager, Artel

by Rodrigues, G., Published in Pharmaceutical Manufacturing, April 2009.

No measurement is perfect and all measurements have some error associated with them. The terms accuracy and precision are often used interchangeably to describe measurement errors in the laboratory. While general usage may be lax at times, in statistical calculations and in regulations, these two terms have different and very distinct meanings. Knowing the definitions and importance of each are critical to the development of a sound laboratory quality control program. As laboratory professionals are placed under increasing regulatory scrutiny, more and more attention is being focused on the accuracy and precision of dispensed volumes.